Who Do 49ers Play In 2025. The kansas city chiefs won the afc west and will visit the 49ers at levi's stadium. See the full 2025 regular season schedule for the san francisco 49ers, including game times, tv channels and ticket information.

The san francisco 49ers have announced their 2025 regular season schedule as well as the opponents and date ranges for the team’s three preseason games. The dallas cowboys and at buffalo — and they also.